It's last night's SpaceX launch of a resupply flight to the space station.
The picture is from about 30 miles south of the launch pad (which gives you some idea where I am). I would have tried for a closer vantage point, but the weather only had a favorable probability of 60%. Those sort of probabilities usually end up as "launch scrubbed followed by rain on the way home."
Unfortunately, the level of activity is not what it once was, but there is still some. This October is unusually active: a global positioning satellite, a ISS supply mission test, and a military launch at the end of the month.